THE MUTANTS MUST STICK TOGETHER AS THEY FIGHT FOR THEIR LIVES — Dr. Campbell attends an anti-mutant summit, attempting to take the Hound program national, and some of the team at Mutant HQ goes on a dangerous mission to stop his efforts. Polaris learns more about her past and makes a crucial decision that could have impactful consequences. Meanwhile, the Mutant HQ comes under attack and, with everything to lose, relationships are put to the test and alliances shift
Four years ago Roderick Campbell is shown with his brother Jack suffering from Cystic fibrosis. Jack's life is almost at an end so Dr. Campbell was unwilling to attend a lecture he have to give but Jack insists that he will be alright. He is then halfway into his lecture speaking about the importance of genes. His years as a scientist have shown him that humans are nothing special for mother nature but are just another species on Earth who have to struggle for survival. He then explains that neanderthals had better chances for being the dominant species on Earth but modern day humans became the one because genes don't have to be destiny, so they stood against them as a society and outgrew their communication. Dr. Campbell further goes on that the evolution have again created a new species (homo superior) with powerful genetic mutations and they may cause the extinction of the modern day humans and they can only survive if they stand together as a species.
Back in the present time the Frost sisters are with the Mutant Underground discussing about how to stop the hound program where the Frost sisters tell John, Lorna, Marcos and Clarice that Dr. Campbell is planning to take the hound program national and the best chance to stop him will be at the the Humanity Today where major anti mutant politicians, business heads and purifiers will be present. When Clarice opposes the idea they claim that they know about Clarice's criminal past, something which they don't know and convince them to help kidnap Campbell at humanity today.
The Struckers are back at the headquarters and are glad to be back home. While they were unpacking john comes into the room and ask Reed if he was able to extract anything useful from Otto Strucker's old research notes and tells them that he will be out for some while to capture Campbell at humanity today. While John is packing for the mission Clarice approaches him and tells him that two years ago she was troubled by some purifiers at Clarke County and she was helped by some members of the Brotherhood which was why she was sent to jail. John gets a little angry at that because she hid such facts from them.
On his way to the summit Dr. Campbell receives a phone call from Mr Wong who tell him that a significant portion of Otto Strucker's research is missing. Campbell tells him to look harder as this is a possible way of wiping out the X gene entirely.
Back at the headquarters Lorna convinces Marcos to cooperate with the frost sisters for her.In the locker Andy is again reading about the von struckers and praises their idea of creating a separate place for mutants while Lauren contradicts saying that they were murderers, they get into an argument when Andy says that the Frost sisters are the only ones here who are telling the truth.
In Charlotte, North Carolina Dr. Campbell and Wolcott arrive at Humanity Today Annual Summit.
In the headquarters Sage finds that Sentinel Services is also tracking everyone Otto Strucker ever worked with and they sending agents to Southern Worldwide Insurance company where Reed's mom work.So the Struckers leave to reach Ellen Strucker before the Sentinel Service agents.In Charlotte the team to capture Campbell arrives at a safe house. The Frost Sisters tell the about it's equipment and inform them that the Hellfire Club founders were the Brotherhood. They begin to prepare to leave within half an hour.
The Struckers arrive at Southern Worldwide and Reed and Caitlin go up the office while Andy and Lauren Stay on guard outside. Ellen was surprised when she received them in her office and they tell her every thing that has been going on since they went on their run and also tell her that her husband is dead.
Before the conference of Humanity today Dr Campbell meets Matthew Montez and tell him that he is trying to expand his efforts at Trask Industries. Montez agrees to talk about this issue and offer help if it will be appropriate. Somewhere in the woods the team captures a billionaire as part of the plan to go inside the conference. At the entrance of southern Worldwide while Andy and Lauren are waiting for their parents two sentinel services agents arrive and Andy attacks them. To stop him from doing further damage Lauren stops him. Annoyed, both use their power against each other and the energy blast created was enough powerful to knock both off their feet. At the moment Reed, Caitlin and Ellen arrive and they all leave.
Back at the summit Dr. Campbell successfully pursues senator Montez to help with the expanded hound program.
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